Re: Hardness Of Tablets
dear Carlo,
If you calculate the tablet deformation energy before breaking in both tests and then equalize those calculated energies, the result gives the correrelation between the two tests that you want.
I think that the 2 test methods give the same breaking force, because the deformation energy and breaking deformation are the same for both cases. (It is the same tablet)
success ■
Teus
Tablet Crushing
I would comment that, assuming the bearing area on the tablet are identical in the two tests, there may still be a difference according to the rate of stress increase as a suddenly applied load from the constant strain device would give rise to a higher stress than a gradually increasing stress. The measured values would clearly indicate any difference and a reconciliation may be possible if the speed of compaction is adjusted on the constant strain device. ■
Hardness of tablets
Hello,
I'm a process engineer form a pharmaceutical company.
I'm actually facing the following problem: we normally measure the hardness of tablet after the compression phase.
My problem is to correlate two different hardness tester: the first one measures hardness by a jaw that, with a constant speed, crushs the tablet (adjust the force in order to have a constant speed) until the tablet breaks; the second one measures hardness by crush the tablet with a linear increasing force until the tablet breaks.
Could you give me any suggestions to correlate theoretically the two different methods?
Many thanks in advance
Carlo Gargiulo
cgargiulo@inwind.it ■