Contained and Automated Method of Ingredient Weighing and Dosing
K-Tron pharmaceutical dispensary systems for the extremely accurate dispensing of active ingredients and excipients to IBC's offer a contained and completely automated method of ingredient weighing and dosing. Each ingredient to the blend can be conveyed via the Premier Pneumatics P-Series vacuum conveyor directly to the K-Tron loss-in-weight feeder for dosing into the appropriate container. Typical dosing systems include several stations, each dedicated to a specific component of the mix. The K-Tron control system can also be designed for several recipes, reflecting different batch weights of each ingredient. Active ingredients can easily be contained simply by integrating active and passive split butterfly valves on the ingredient pickup and discharge points.
Experienced in providing such dispensary projects, K-Tron incorporates its own feeding, pneumatic conveying and controls technology and out sources and engineers additional equipment as needed. Projects have ranged in size from small to quite large. Validation documentation can be provided with the project.
Automated dispensing systems are utilized throughout the pharmaceutical industry for the metering of excipients, Active Pharmaceutical Ingredients ( APIs ) and lubricants into Intermediate Bulk Containers ( IBCs ) and other large storage vessels. Typically, these dispensaries serve as an intermediate production stage to formulate the blend prior to the granulation process. In most pharmaceutical plants, separate broaching areas are established for receiving raw materials from suppliers or other plants. These broaching areas usually include the unloading of pallets containing drums or boxes, or the unloading of super sacks. The contents of each container are transferred via either gravity flow or pneumatic conveying to the dispensary area for the loading of IBCs.
Once the materials are transferred to the dispensary area, loss-in-weight ( LIW ) feeders are used to regulate and meter the correct ingredient amount into the receiving IBC. Some ingredients may represent only a fraction of the total batch weight for a specific recipe. LIW feeders that offer extremely high short- term accuracy are critical in assuring the correct amount is metered.
In the case of a single material loading, as in excipients, the material may be conveyed under either dense phase or dilute phase vacuum via Premier Pneumatics vacuum receivers to a separate hopper mounted above the K-Tron loss-in-weight feeder. In cases where a pre-mixed formulation includes a potent API, containment is required. In this case the outlet of the IBC or the loader hopper is equipped with a butterfly valve or a split butterfly valve, depending upon the level of containment required.
In cases where several ingredients are metered into the same IBC, automated guide vehicles (AGV) can be used to transport the IBC between each dispensary station. K-Tron can supply either loss-in-weight or gain-in-weight batching systems for this application.
About K-Tron:
K-Tron is a global leader in the gravimetric feeder market and a one-source solution for feeding, pneumatic conveying and systems engineering solutions. The K-Tron Process Group manufactures and markets its equipment for the process industries under the brand names of K-Tron Feeders and Premier Pneumatics.
Ingredient Weighing & Dosing
May 24, 2007
K-Tron Pharmaceutical Dispensary Systems Offer
Contained and Automated Method of Ingredient Weighing and Dosing
K-Tron pharmaceutical dispensary systems for the extremely accurate dispensing of active ingredients and excipients to IBC's offer a contained and completely automated method of ingredient weighing and dosing. Each ingredient to the blend can be conveyed via the Premier Pneumatics P-Series vacuum conveyor directly to the K-Tron loss-in-weight feeder for dosing into the appropriate container. Typical dosing systems include several stations, each dedicated to a specific component of the mix. The K-Tron control system can also be designed for several recipes, reflecting different batch weights of each ingredient. Active ingredients can easily be contained simply by integrating active and passive split butterfly valves on the ingredient pickup and discharge points.
Experienced in providing such dispensary projects, K-Tron incorporates its own feeding, pneumatic conveying and controls technology and out sources and engineers additional equipment as needed. Projects have ranged in size from small to quite large. Validation documentation can be provided with the project.
Automated dispensing systems are utilized throughout the pharmaceutical industry for the metering of excipients, Active Pharmaceutical Ingredients ( APIs ) and lubricants into Intermediate Bulk Containers ( IBCs ) and other large storage vessels. Typically, these dispensaries serve as an intermediate production stage to formulate the blend prior to the granulation process. In most pharmaceutical plants, separate broaching areas are established for receiving raw materials from suppliers or other plants. These broaching areas usually include the unloading of pallets containing drums or boxes, or the unloading of super sacks. The contents of each container are transferred via either gravity flow or pneumatic conveying to the dispensary area for the loading of IBCs.
Once the materials are transferred to the dispensary area, loss-in-weight ( LIW ) feeders are used to regulate and meter the correct ingredient amount into the receiving IBC. Some ingredients may represent only a fraction of the total batch weight for a specific recipe. LIW feeders that offer extremely high short- term accuracy are critical in assuring the correct amount is metered.
In the case of a single material loading, as in excipients, the material may be conveyed under either dense phase or dilute phase vacuum via Premier Pneumatics vacuum receivers to a separate hopper mounted above the K-Tron loss-in-weight feeder. In cases where a pre-mixed formulation includes a potent API, containment is required. In this case the outlet of the IBC or the loader hopper is equipped with a butterfly valve or a split butterfly valve, depending upon the level of containment required.
In cases where several ingredients are metered into the same IBC, automated guide vehicles (AGV) can be used to transport the IBC between each dispensary station. K-Tron can supply either loss-in-weight or gain-in-weight batching systems for this application.
About K-Tron:
K-Tron is a global leader in the gravimetric feeder market and a one-source solution for feeding, pneumatic conveying and systems engineering solutions. The K-Tron Process Group manufactures and markets its equipment for the process industries under the brand names of K-Tron Feeders and Premier Pneumatics.
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https://edir.bulk-online.com/profile...ion-k-tron.htm
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