Given the trend for ever increasing potency of pharmaceutical powders, project engineers are continually faced with the challenge of upgrading the containment of charging to an existing vessel.
For many years the PSL ChargePoint has been widely used in the pharmaceutical industry for charging APIs (active potent ingredients) into reactor vessels in a contained manner, achieving OELs of <1mg/m3 TWA 8hours, 1 hour operation.
When containing solids transfer to existing plant equipment, you can often be faced with upgrading a reactor with no free nozzles available.
A highly efficient resolution is to use the existing sight glass nozzle on the reactor and replace with a PSL ChargePoint Active – enabling multifunctional capabilities. The PSL ChargePoint can then be used for contained charging from bags or bottles, or to view inside the reactor using the novel PSL ChargePoint Sight Glass attachment. The sight glass mimics the ChargePoint passive, maintaining containment whilst providing a wide area for safe viewing into the reactor. The sight glass adapter can be used from full vacuum up to 6 BarG pressure in both open and closed positions.
PSL can supply a range of accessories including CIP systems for both the ChargePoint and the reactor itself. This maximises the use and efficiency of often limited nozzles, providing multi functionality for a single nozzle.
Powder Systems Ltd.
May 23, 2005
Need to upgrade for API Charging?
Multifunctional PSL ChargePoint enables contained charging, sight glass & CIP
Given the trend for ever increasing potency of pharmaceutical powders, project engineers are continually faced with the challenge of upgrading the containment of charging to an existing vessel.
For many years the PSL ChargePoint has been widely used in the pharmaceutical industry for charging APIs (active potent ingredients) into reactor vessels in a contained manner, achieving OELs of <1mg/m3 TWA 8hours, 1 hour operation.
When containing solids transfer to existing plant equipment, you can often be faced with upgrading a reactor with no free nozzles available.
A highly efficient resolution is to use the existing sight glass nozzle on the reactor and replace with a PSL ChargePoint Active – enabling multifunctional capabilities. The PSL ChargePoint can then be used for contained charging from bags or bottles, or to view inside the reactor using the novel PSL ChargePoint Sight Glass attachment. The sight glass mimics the ChargePoint passive, maintaining containment whilst providing a wide area for safe viewing into the reactor. The sight glass adapter can be used from full vacuum up to 6 BarG pressure in both open and closed positions.
PSL can supply a range of accessories including CIP systems for both the ChargePoint and the reactor itself. This maximises the use and efficiency of often limited nozzles, providing multi functionality for a single nozzle.
For more information, please visit:
https://edir.bulk-online.com/profile...er-systems.htm
Attachments
powder-_systems_may-2005 (GIF)
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